Publications

OIRM scientists have been busy publishing their research findings. Below is a sample of their work. This page is updated every month.

Arulmozhivarman G, Kräter M, Wobus M, Friedrichs J, Bejestani EP, Müller K, Lambert K, Alexopoulou D, Dahl A, Stöter M, Bickle M, Shayegi N, Hampe J, Stölzel F, Brand M, von Bonin M, Bornhäuser M. Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells. Sci Rep. 2017 Sep 21;7(1):12084. doi: 10.1038/s41598-017-12360-0. http://www.ncbi.nlm.nih.gov/pubmed/28935977

Barrera-Ramirez J, Lavoie JR, Maganti HB, Stanford WL, Ito C, Sabloff M, Brand M, Rosu-Myles M, Le Y, Allan DS. Micro-RNA Profiling of Exosomes from Marrow-Derived Mesenchymal Stromal Cells in Patients with Acute Myeloid Leukemia: Implications in Leukemogenesis. Stem Cell Rev. 2017 Sep 16. doi: 10.1007/s12015-017-9762-0. http://www.ncbi.nlm.nih.gov/pubmed/28918518

Feinberg K, Kolaj A, Wu C, Grinshtein N, Krieger JR, Moran MF, Rubin LL, Miller FD, Kaplan DR. A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria. J Cell Biol. 2017 Sep 6. pii: jcb.201705085. doi: 10.1083/jcb.201705085. http://www.ncbi.nlm.nih.gov/pubmed/28877995

Han H, Braunschweig U, Gonatopoulos-Pournatzis T, Weatheritt RJ, Hirsch CL, Ha KC, Radovani E, Nabeel-Shah S, Sterne-Weiler T, Wang J, O'Hanlon D, Pan Q, Ray D, Zheng H, Vizeacoumar F, Datti A, Magomedova L, Cummins CL, Hughes TR, Greenblatt JF, Wrana JL, Moffat J, Blencowe BJ. Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors. Mol Cell. 2017 Feb 2;65(3):539-553.e7. doi: 10.1016/j.molcel.2017.01.011. http://www.ncbi.nlm.nih.gov/pubmed/28157508

Kang M, Thébaud B. Stem cell biology and regenerative medicine for neonatal lung diseases. Pediatr Res. 2017 Sep 18. doi: 10.1038/pr.2017.232. http://www.ncbi.nlm.nih.gov/pubmed/28922348

Keane C, Jerkic M, Laffey JG. Stem Cell-based Therapies for Sepsis. Anesthesiology. 2017 Sep 5. doi: 10.1097/ALN.0000000000001882. http://www.ncbi.nlm.nih.gov/pubmed/28872482

Lan X, Jörg DJ, Cavalli FMG, Richards LM, Nguyen LV, Vanner RJ, Guilhamon P, Lee L, Kushida MM, Pellacani D, Park NI, Coutinho FJ, Whetstone H, Selvadurai HJ, Che C, Luu B, Carles A, Moksa M, Rastegar N, Head R, Dolma S, Prinos P, Cusimano MD, Das S, Bernstein M, Arrowsmith CH, Mungall AJ, Moore RA, Ma Y, Gallo M, Lupien M, Pugh TJ, Taylor MD, Hirst M, Eaves CJ, Simons BD, Dirks PB. Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy. Nature. 2017 Aug 30. doi: 10.1038/nature23666. http://www.ncbi.nlm.nih.gov/pubmed/28854171

Lorusso D, Nikolov HN, Milner JS, Ochotny NM, Sims SM, Dixon SJ, Holdsworth DW. Practical fabrication of microfluidic platforms for live-cell microscopy. Biomed Microdevices. 2016 Oct;18(5):78. doi: 10.1007/s10544-016-0101-z. http://www.ncbi.nlm.nih.gov/pubmed/27523472

Mothe AJ, Tassew NG, Shabanzadeh AP, Penheiro R, Vigouroux RJ, Huang L, Grinnell C, Cui YF, Fung E, Monnier PP, Mueller BK, Tator CH. RGMa inhibition with human monoclonal antibodies promotes regeneration, plasticity and repair, and attenuates neuropathic pain after spinal cord injury. Sci Rep. 2017 Sep 5;7(1):10529. doi: 10.1038/s41598-017-10987-7. http://www.ncbi.nlm.nih.gov/pubmed/28874746

Nadkarni RR, Abed S, Cox BJ, Bhatia S, Lau JT, Surette MG, Draper JS. Functional Enterospheres Derived In Vitro from Human Pluripotent Stem Cells. Stem Cell Reports. 2017 Aug 24. pii: S2213-6711(17)30334-X. doi: 10.1016/j.stemcr.2017.07.024. http://www.ncbi.nlm.nih.gov/pubmed/288673

Nguyen MA, Karunakaran D, Geoffrion M, Cheng HS, Tandoc K, Perisic Matic L, Hedin U, Maegdefessel L, Fish JE, Rayner KJ. Extracellular Vesicles Secreted by Atherogenic Macrophages Transfer MicroRNA to Inhibit Cell Migration. Arterioscler Thromb Vasc Biol. 2017 Sep 7. pii: ATVBAHA.117.309795. doi: 10.1161/ATVBAHA.117.309795. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/28882869

Nori S, Ahuja CS, Fehlings MG. Translational Advances in the Management of Acute Spinal Cord Injury: What is New? What is Hot? Neurosurgery. 2017 Sep 1;64(CN_suppl_1):119-128. doi: 10.1093/neuros/nyx217. http://www.ncbi.nlm.nih.gov/pubmed/28899041

Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB. ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells. Cell Stem Cell. 2017 Sep 7;21(3):411. doi: 10.1016/j.stem.2017.08.008. No abstract available. http://www.ncbi.nlm.nih.gov/pubmed/28886368

Rusiecki D, Lach B, Manoranjan B, Fleming A, Ajani O, Singh SK. Progression of atypical extraventricular neurocytoma to anaplastic ganglioglioma. Hum Pathol. 2017 Jan;59:125-130. doi: 10.1016/j.humpath.2016.08.007. Epub 2016 Sep 3. http://www.ncbi.nlm.nih.gov/pubmed/27597523

Shojaie S, Lee J, Wang J, Ackerley C, Post M. Generation of ESC-derived Mouse Airway Epithelial Cells Using Decellularized Lung Scaffolds. J Vis Exp. 2016 May 5;(111). doi: 10.3791/54019. http://www.ncbi.nlm.nih.gov/pubmed/27214388

Steinbach SK, Yau TM, Ouzounian M, Abdel-Qadir H, Chandy M, Waddell TK, Husain M. Skin-derived precursors from human subjects with Type 2 diabetes yield dysfunctional vascular smooth muscle cells. Clin Sci (Lond). 2017 Jul 5;131(15):1801-1814. doi: 10.1042/CS20170239. Print 2017 Aug 1. http://www.ncbi.nlm.nih.gov/pubmed/28424290

Takebe T, Zhang B, Radisic M. Synergistic Engineering: Organoids Meet Organs-on-a-Chip. Cell Stem Cell. 2017 Sep 7;21(3):297-300. doi: 10.1016/j.stem.2017.08.016. http://www.ncbi.nlm.nih.gov/pubmed/28886364

Tewary M, Ostblom J, Prochazka L, Zulueta-Coarasa T, Shakiba N, Fernandez-Gonzalez R, Zandstra PW. A stepwise model of Reaction-Diffusion and Positional-Information governs self-organized human peri-gastrulation-like patterning. Development. 2017 Sep 4. pii: dev.149658. doi: 10.1242/dev.149658. http://www.ncbi.nlm.nih.gov/pubmed/28870989

Varga B, Nagy A. Isolation, Propagation, and Differentiation of Radial Glia-Like Neural Progenitor Cells in Adherent Cultures. Cold Spring Harb Protoc. 2017 Sep 1;2017(9):pdb.prot094177. doi: 10.1101/pdb.prot094177. http://www.ncbi.nlm.nih.gov/pubmed/28864570

Zhang X, Bendeck MP, Simmons CA, Santerre JP. Deriving vascular smooth muscle cells from mesenchymal stromal cells: Evolving differentiation strategies and current understanding of their mechanisms. Biomaterials. 2017 Aug 15;145:9-22. doi: 10.1016/j.biomaterials.2017.08.028. [Epub ahead of print] Review. http://www.ncbi.nlm.nih.gov/pubmed/28843066