OIRM scientists have been busy publishing their research findings. Below is a sample of their work. This page is updated every month.

  • Barron CC, Lalu MM, Stewart DJ, Fergusson D, Yang H, Moher D, Liu P, Mazer D, Devereaux PJ, McIntyre L; Canadian Perioperative Anesthesia Clinical Trials Group. Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol. Syst Rev. 2017 Nov 7;6(1):226. doi: 10.1186/s13643-017-0601-9.
  • Chisholm J1, Bhatt S1, Chaboureau A1, Viswanathan S2. Strategy for an abbreviated in-house qualification of a commercially available Rapid Microbiology Method (RMM) for canadian regulatory approval. Cytotherapy. 2017 Oct 20. doi: 10.1016/j.jcyt.2017.09.004.
  • Deol GSJ, Cuthbert TN, Gatie MI, Spice DM, Hilton LR, Kelly GM. Wnt and Hedgehog Signaling Regulate the Differentiation of F9 Cells into Extraembryonic Endoderm. Front Cell Dev Biol. 2017 Oct 25;5:93. doi: 10.3389/fcell.2017.00093. eCollection 2017.
  • Führmann T, Anandakumaran P, Payne S, Pakulska M, Varga BV, Nagy A, Tator C, Shoichet MS. Combined delivery of chondroitinase ABC and human induced pluripotent stem cell-derived neuroepithelial cells promote tissue repair in an animal model of spinal cord injury. Biomed Mater. 2017 Oct 30. doi: 10.1088/1748-605X/aa96dc.
  • Hernández-Hernández JM, García-González EG, Brun CE, Rudnicki MA. The Myogenic Regulatory Factors, Determinants of Muscle Development, Cell Identity and Regeneration. Semin Cell Dev Biol. 2017 Nov 7. doi: 10.1016/j.semcdb.2017.11.010. Review.
  • He X, Lindsay-Mosher N, Li Y, Molinaro AM, Pellettieri J, Pearson BJ. FOX and ETS family transcription factors regulate the pigment cell lineage in planarians. Development. 2017 Nov 20. doi: 10.1242/dev.156349.
  • Grol MW, Brooks PJ, Pereverzev A, Dixon SJ. P2X7 nucleotide receptor signaling potentiates the Wnt/β-catenin pathway in cells of the osteoblast lineage. Purinergic Signal. 2016 Sep;12(3):509-20. doi: 10.1007/s11302-016-9517-4. Epub 2016 May 21.
  • Iu J, Santerre JP, Kandel RA. Towards Engineering Distinct Multi-lamellated Outer and Inner Annulus Fibrosus Tissues. J Orthop Res. 2017 Oct 31. doi: 10.1002/jor.23793.
  • Laaper M, Haque T, Slack RS, Jahani-Asl A. Modeling Neuronal Death and Degeneration in Mouse Primary Cerebellar Granule Neurons. J Vis Exp. 2017 Nov 6;(129). doi: 10.3791/55871.
  • Martewicz S, Serena E, Zatti S, Keller G, Elvassore N. Substrate and mechanotransduction influence SERCA2a localization in human pluripotent stem cell-derived cardiomyocytes affecting functional performance. Stem Cell Res. 2017 Oct 16;25:107-114. doi: 10.1016/j.scr.2017.10.011.
  • Protic O, Islam MS, Greco S, Giannubilo SR, Lamanna P, Petraglia F, Ciavattini A, Castellucci M, Hinz B, Ciarmela P. Activin A in Inflammation, Tissue Repair, and Fibrosis: Possible Role as Inflammatory and Fibrotic Mediator of Uterine Fibroid Development and Growth. Semin Reprod Med. 2017 Nov;35(6):499-509. doi: 10.1055/s-0037-1607265. Epub 2017 Nov 3.
  • Rafatian G, Davis DR. The Frustration and Futility of Intracoronary Stem Cell Therapy. Can J Cardiol. 2017 Oct 5. doi: 10.1016/j.cjca.2017.09.023.
  • Rashedi I, Talele N, Wang XH, Hinz B, Radisic M, Keating A. Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells. PLoS One. 2017 Oct 31;12(10):e0187348. doi: 10.1371/journal.pone.0187348. eCollection 2017.
  • Williams BA, Law AD, Routy B, den Hollander N. Gupta V, Wang XH,Chaboureau A1, Viswanathan S1, Keating A. A phase I trial of NK-92 cells for refractory hematological malignancies relapsing after autologous hematopoietic cell transplantation shows safety and evidence of efficacy. Oncotarget. 2017 Jul 12;8(51):89256-89268. doi: 10.18632/oncotarget.19204. eCollection 2017 Oct 24.