Publications

OIRM scientists have been busy publishing their research findings. Below is a sample of their work. This page is updated every month.

  • Behringer R, Gertsenstein M, Nagy KV, Nagy A. Cold Spring Harb Protoc. Shipment of Live Preimplantation-Stage Mouse Embryos. 2017 May 1;2017(5):pdb.prot092742. doi: 10.1101/pdb.prot092742. http://www.ncbi.nlm.nih.gov/pubmed/28461656

  • Brunette I, Roberts CJ, Vidal F, Harissi-Dagher M, Lachaine J, Sheardown H, Durr GM, Proulx S, Griffith M. Alternatives to eye bank native tissue for corneal stromal replacement. Prog Retin Eye Res. 2017 Apr 24. doi: 10.1016/j.preteyeres.2017.04.002. http://www.ncbi.nlm.nih.gov/pubmed/28450146

  • Catapano J, Zhang J, Scholl D, Chiang C, Gordon T, Borschel GH. N-Acetylcysteine Prevents Retrograde Motor Neuron Death after Neonatal Peripheral Nerve Injury. Plast Reconstr Surg. 2017 May;139(5):1105e-1115e. doi: 10.1097/PRS.0000000000003257. http://www.ncbi.nlm.nih.gov/pubmed/28445364

  • Coles BLK, van der Kooy D. P-Cadherin is necessary for retinal stem cell behavior in vitro, but not in vivo. Stem Cell Res. 2017 May 3;21:141-147. doi: 10.1016/j.scr.2017.05.001. http://www.ncbi.nlm.nih.gov/pubmed/28494434

  • Davies JE, Walker JT, Keating A. Concise Review: Wharton's Jelly: The Rich, but Enigmatic, Source of Mesenchymal Stromal Cells. Stem Cells Transl Med. 2017 May 10. doi: 10.1002/sctm.16-0492. http://www.ncbi.nlm.nih.gov/pubmed/28488282

  • Kan Y, Batada NN, Hendrickson EA. Human somatic cells deficient for RAD52 are impaired for viral integration and compromised for most aspects of homology-directed repair. DNA Repair (Amst). 2017 May 10;55:64-75. doi: 10.1016/j.dnarep.2017.04.006. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/28549257

  • Karimzadeh F, Opas M. Calreticulin Is Required for TGF-β-Induced Epithelial-to-Mesenchymal Transition during Cardiogenesis in Mouse Embryonic Stem Cells. Stem Cell Reports. 2017 Apr 13.  doi: 10.1016/j.stemcr.2017.03.018. http://www.ncbi.nlm.nih.gov/pubmed/28434939

  • Kornmuller A, Brown CFC, Yu C, Flynn LE. Fabrication of Extracellular Matrix-derived Foams and Microcarriers as Tissue-specific Cell Culture and Delivery Platforms. J Vis Exp. 2017 Apr 11;(122). doi: 10.3791/55436. https://www.ncbi.nlm.nih.gov/pubmed/28447989

  • Levi AD, Okonkwo DO, Park P, Jenkins AL 3rd, Kurpad SN, Parr AM, Ganju A, Aarabi B, Kim D, Casha S, Fehlings MG, Harrop JS, Anderson KD, Gage A, Hsieh J, Huhn S, Curt A, Guzman R. Emerging Safety of Intramedullary Transplantation of Human Neural Stem Cells in Chronic Cervical and Thoracic Spinal Cord Injury. Neurosurgery. 2017 May 24. doi: 10.1093/neuros/nyx250. http://www.ncbi.nlm.nih.gov/pubmed/28541431

  • Liang W, Lu A, Davis DR. Induced Pluripotent Stem Cell-Based Treatment of Acquired Heart Block: The Battle for Tomorrow Has Begun! Circ Arrhythm Electrophysiol. 2017 May;10(5):e005331. http://www.ncbi.nlm.nih.gov/pubmed/28500180

  • Möbius MA, Thébaud B. Bronchopulmonary Dysplasia - Where have all the Stem Cells gone? Origin and (potential) function of resident lung stem cells. Chest. 2017 May 4. doi: 10.1016/j.chest.2017.04.173. https://www.ncbi.nlm.nih.gov/pubmed/28479114

  • Nieborowska-Skorska M, Sullivan K, Dasgupta Y, Podszywalow-Bartnicka P, Hoser G, Maifrede S, Martinez E, Di Marcantonio D, Bolton-Gillespie E, Cramer-Morales K, Lee J, Li M, Slupianek A, Gritsyuk D, Cerny-Reiterer S, Seferynska I, Stoklosa T, Bullinger L, Zhao H, Gorbunova V, Piwocka K, Valent P, Civin CI, Muschen M, Dick JE, Wang JCY, Bhatia S, Bhatia R, Eppert K, Minden MD, Sykes SM, Skorski T. Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells. J Clin Invest. 2017 May 8. doi: 10.1172/JCI90825. http://www.ncbi.nlm.nih.gov/pubmed/28481221

  • Noman AS, Uddin M, Chowdhury AA, Nayeem MJ, Raihan Z, Rashid MI, Azad AK, Rahman ML, Barua D, Sultana A, Shirin A, Ferdous J, Parag RR, Rahman SM, Mahmud MR, Jerin CS, Jahan N, Siddiqua A, Ara T, Sabur EB, Alam SS, Baidya S, Akther S, Rahman MZ, Banu T, Murugan AK, Sabri S, Islam SMS, Karakas B, Aboussekhra A, Yeger H, Farhat WA, Islam SS. Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer. Sci Rep. 2017 May 11;7(1):1796. doi: 10.1038/s41598-017-01268-4.http://www.ncbi.nlm.nih.gov/pubmed/28496132

  • Pakulska MM, Tator CH, Shoichet MS. Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1α promotes functional repair in the injured rat spinal cord. Biomaterials. 2017 Apr 18;134:13-21. doi: 10.1016/j.biomaterials.2017.04.016. http://www.ncbi.nlm.nih.gov/pubmed/28453954

  • Rahman N, Brauer PM, Ho L, Usenko T, Tewary M, Zúñiga-Pflücker JC, Zandstra PW. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence. Nat Commun. 2017 May 25;8:15380. doi: 10.1038/ncomms15380. http://www.ncbi.nlm.nih.gov/pubmed/28541275

  • Ravindran E, Hu H, Yuzwa SA, Hernandez-Miranda LR, Kraemer N, Ninnemann O, Musante L, Boltshauser E, Schindler D, Hübner A, Reinecker HC, Ropers HH, Birchmeier C, Miller FD, Wienker TF, Hübner C, Kaindl AM. Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation. PLoS Genet. 2017 Apr 28;13(4):e1006746. doi: 10.1371/journal.pgen.1006746. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/28453519

  • Shridhar A, Gillies E, Amsden BG, Flynn LE. Composite Bioscaffolds Incorporating Decellularized ECM as a Cell-Instructive Component Within Hydrogels as In Vitro Models and Cell Delivery Systems. Methods Mol Biol. 2017 May 11. doi: 10.1007/7651_2017_36. http://www.ncbi.nlm.nih.gov/pubmed/28493212

  • Shridhar A, Gillies E, Amsden BG, Flynn LE. Composite Bioscaffolds Incorporating Decellularized ECM as a Cell-Instructive Component Within Hydrogels as In Vitro Models and Cell Delivery Systems. Methods Mol Biol. 2017 May 11. doi: 10.1007/7651_2017_36. http://www.ncbi.nlm.nih.gov/pubmed/28493212

  • Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holländer GA, Zúñiga-Pflücker JC, Tolar J, Blazar BR. T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. JCI Insight. 2017 May 18;2(10). pii: 92056. doi: 10.1172/jci.insight.92056. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/28515359

  • Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holländer GA, Zúñiga-Pflücker JC, Tolar J, Blazar BR. T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. JCI Insight. 2017 May 18;2(10). pii: 92056. doi: 10.1172/jci.insight.92056. http://www.ncbi.nlm.nih.gov/pubmed/28515359

  • Snyder JS, Cahill SP, Frankland PW. Running promotes spatial bias independently of adult neurogenesis. Hippocampus. 2017 May 5. doi: 10.1002/hipo.22737. http://www.ncbi.nlm.nih.gov/pubmed/28474795

  • Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ. Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 2017 May 17. doi: 10.1038/nature22370. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/28514439

  • Sun X, Nunes SS. Maturation of Human Stem Cell-derived Cardiomyocytes in Biowires Using Electrical Stimulation. J Vis Exp. 2017 May 6;(123). doi: 10.3791/55373. http://www.ncbi.nlm.nih.gov/pubmed/28518082

  • Usprech J, Romero DA, Amon CH, Simmons CA. Combinatorial screening of 3D biomaterial properties that promote myofibrogenesis for mesenchymal stromal cell-based heart valve tissue engineering. Acta Biomater. 2017 May 19. pii: S1742-7061(17)30335-5. doi: 10.1016/j.actbio.2017.05.044. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/28532900

  • Voronova A, Yuzwa SA, Wang BS, Zahr S, Syal C, Wang J, Kaplan DR, Miller FD. Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain. Neuron. 2017 May 3;94(3):500-516.e9. doi: 10.1016/j.neuron.2017.04.018. http://www.ncbi.nlm.nih.gov/pubmed/28472653

  • Voura EB, Montalvo MJ, Dela Roca KT, Fisher JM, Defamie V, Narala SR, Khokha R, Mulligan ME, Evans CA. Planarians as models of cadmium-induced neoplasia provide measurable benchmarks for mechanistic studies. Ecotoxicol Environ Saf. 2017 May 5;142:544-554. doi: 10.1016/j.ecoenv.2017.04.044. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/28482323

  • Wen J, Tao H, Lau K, Liu H, Simmons CA, Sun Y, Hopyan S. Cell and Tissue Scale Forces Coregulate Fgfr2-Dependent Tetrads and Rosettes in the Mouse Embryo. Biophys J. 2017 May 23;112(10):2209-2218. doi: 10.1016/j.bpj.2017.04.024. http://www.ncbi.nlm.nih.gov/pubmed/28538157

  • Xu W, Lakshman N, Morshead CM. Building a central nervous system: The neural stem cell lineage revealed. Neurogenesis (Austin). 2017 Apr 28;4(1):e1300037. doi: 10.1080/23262133.2017.1300037. eCollection 2017. Review. http://www.ncbi.nlm.nih.gov/pubmed/28516107