Profile and Department: Assistant Professor, Chemical Engineering and Applied Chemistry
Physiologically relevant, personalized, tissue mimetic systems offer the opportunity to systematically dissect fundamental mechanisms of tissue assembly and disease to allow identification of novel therapy targets to manipulate these processes for therapeutic benefit. Furthermore, such systems offer the potential to classify the effectiveness of drugs in specific patients for the design of personalized therapies. Our mission in the McGuigan lab is to use tissue engineering strategies to assemble multicellular tissue mimetic platforms that are both physiologically relevant and allow acquisition of high value data for both drug discovery and fundamental research. Our research team is focused on understanding how to generate relevant tissue architectures that enable isolation of predictive data from specific cell populations within heterogeneous tissue systems.