Profile and Department: Associate Professor, Chemical Engineering, University of Waterloo
The objective of Regenerative Nanomedicine Lab focuses on understanding and optimizing the microenvironment, especially cell-topography interactions, for regenerative medicine applications with translation as the eventual goal. Our research group is interested to study the modulation of cell behavior by nanotopography for: (1) Topography-regulation of adult and pluripotent stem cells lineage commitment and differentiation; (2) Biomaterial approach to study ex-vivo pluripotent stem cell expansion and (3) Application of nano-structure for biomedical applications in vascular, neural and cornea tissue engineering. Our multidisciplinary research has been enabled by close collaborations with clinicians, material scientists, engineers, biophysicists and cell biologists. We aspire to study the nano-topography-regulation of cell behaviour to apply the nanotopography regulation in translational research and clinical applications, and to seek mechanistic understanding of the mechanobiology of the cell behaviors.