OIRM supports cell therapy clinical trials in Ontario through funding for its large Disease Teams program. Currently, OIRM is directly supporting one clinical trial (septic shock) and several other research projects where clinical trials may launch in 1-4 years. Through programs and workshops led by OIRM’s Clinical Translation Initiative, we help build capacity and expertise for new clinical trials to find success in the future.
In addition, through the ongoing research at The Ottawa Hospital, a small number of patients with severe autoimmune diseases have been treated using chemotherapy and blood stem cell transplants outside of clinical trials and supported through the provincial health care system. The diseases are:
- Multiple sclerosis (see lay summary and research paper)
- Myasthenia gravis (see lay summary and research paper)
- Scleroderma (see patient story; procedure based on European clinical trial)
- Stiff person syndrome (see patient story and research paper)
If you are a patient or caregiver seeking information about clinical trials, we recommend you review our About Clinical Trials page. For more information about current and upcoming clinical trials in Ontario, see the list below.
Current Ontario clinical trials
This trial listing is also available in the graphic format for download and sharing. Click the icon below.
Trials launching soon:
|Lauralyn McIntyre – OHRI||Cellular immunotherapy for septic shock (CISS): A Phase II Multicenter Clinical Trial||Septic Shock||II|
|Don Mabbot – SickKids||Metformin for brain repair in children with Cerebral Palsy||Cerebral Palsy||II|
|Don Mabbot and Freda Miller – SickKids||Metformin to stimulate brain repair in children with Multiple Sclerosis||Multiple Sclerosis||II|
Recently completed trials:
|Lauralyn McIntyre – OHRI||Cellular immunotherapy for septic shock (CISS): A Phase I Trial||Septic Shock||I|
|Terrence Yau – UHN||IMPACT-CABG Trial: IMPlantation of Autologous CD133+ sTem Cells in Patients Undergoing Coronary Artery Bypass Grafting (IMPACT-CABG)||Heart Failure||II|