David O’Gorman
Profile and Department: Scientist, Lawson Health Research Institute
Research Interests:
My research program is based in the Roth McFarlane Hand and Upper Limb Centre, the largest hand and upper limb surgical unit in Canada. My research interests include the development of 3D human cell-based tissue mimetics to model normal and abnormal connective tissue repair diseases of the hand and upper limb. These include bio-mimetics of Dupuytren’s disease, a common and heritable fibro-proliferative condition of the palmar fascia, and (more recently) bio-mimetics of Rotator Cuff Disease, an extremely common, aging related condition characterized by lack of supraspinatus tendon integrity. I am also interested in developing 3D co-culture models of rotator cuff infection, specifically with Propionibacterium acnes.