Profile and Department: Assistant Professor, Pathology, University Health Network
Dr. Diamandis’ Lab focuses on modernizing traditional phenotypic readouts of human neurological diseases. Specifically, they are leveraging artificial intelligence (AI) and deep learning to carry out large-scale morphologic analyses of neurological disorders not practical by human observers. Similarly, they use mass spectrometry-based proteomics to provide global protein-based profiles of normal brain development and disease. They use these rich datasets as a discovery resource to guide more focused mechanistic studies in neural stem cell and cerebral organoid culture systems. Together, these tools aim to improve our understanding of the human brain and lead to the development of novel therapies for neurological disorders.