Samuel Asfaha

Nicolas Pinault

Profile and Department: Assistant Professor, Schulich School of Medicine and Dentistry, Western University

Research Interests:

Our research focuses on identifying the cellular origin of colorectal cancer by characterizing the intestinal and colonic stem cells of the gut. We are focused on understanding the fundamental processes regulating normal and mutated intestinal/colonic stem cells and aim to define the role of these stem cells in tissue regeneration and carcinogenesis. We utilize a range of approaches from transgenic mouse models to in vitro “mini-guts” to elucidate the key pathways important in cancer and tissue repair.

PubMed Research Publications